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Lee Josephson
Lee Josephson
Massachusetts General Hospital
E-mail confirmado em medchemimaging.com
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Ultrasmall superparamagnetic iron oxide: characterization of a new class of contrast agents for MR imaging.
R Weissleder, G Elizondo, J Wittenberg, CA Rabito, HH Bengele, ...
Radiology 175 (2), 489-493, 1990
13601990
High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates
L Josephson, CH Tung, A Moore, R Weissleder
Bioconjugate chemistry 10 (2), 186-191, 1999
12371999
Cell-specific targeting of nanoparticles by multivalent attachment of small molecules
R Weissleder, K Kelly, EY Sun, T Shtatland, L Josephson
Nature biotechnology 23 (11), 1418-1423, 2005
10962005
Vanadate is a potent (Na, K)-ATPase inhibitor found in ATP derived from muscle.
LC Cantley Jr, L Josephson, R Warner, M Yanagisawa, C Lechene, ...
Journal of Biological Chemistry 252 (21), 7421-7423, 1977
10541977
Magnetic relaxation switches capable of sensing molecular interactions
JM Perez, L Josephson, T O'Loughlin, D Högemann, R Weissleder
Nature biotechnology 20 (8), 816-820, 2002
10382002
A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation
MF Kircher, U Mahmood, RS King, R Weissleder, L Josephson
Cancer research 63 (23), 8122-8125, 2003
7322003
Viral-induced self-assembly of magnetic nanoparticles allows the detection of viral particles in biological media
JM Perez, FJ Simeone, Y Saeki, L Josephson, R Weissleder
Journal of the American Chemical Society 125 (34), 10192-10193, 2003
6702003
A characterization of vanadate interactions with the (Na, K)-ATPase. Mechanistic and regulatory implications
LC Cantley Jr, LG Cantley, L Josephson
The Journal of biological chemistry 253 (20), 7361-7368, 1978
6701978
Ultrasmall superparamagnetic iron oxide: an intravenous contrast agent for assessing lymph nodes with MR imaging.
R Weissleder, G Elizondo, J Wittenberg, AS Lee, L Josephson, TJ Brady
Radiology 175 (2), 494-498, 1990
6281990
Detection of vascular adhesion molecule-1 expression using a novel multimodal nanoparticle
KA Kelly, JR Allport, A Tsourkas, VR Shinde-Patil, L Josephson, ...
Circulation research 96 (3), 327-336, 2005
5712005
Magnetic nanosensors for the detection of oligonucleotide sequences
L Josephson, JM Perez, R Weissleder
Angewandte Chemie 113 (17), 3304-3306, 2001
5302001
Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes
L Josephson, MF Kircher, U Mahmood, Y Tang, R Weissleder
Bioconjugate chemistry 13 (3), 554-560, 2002
4762002
In vivo high resolution three-dimensional imaging of antigen-specific cytotoxic T-lymphocyte trafficking to tumors
MF Kircher, JR Allport, EE Graves, V Love, L Josephson, AH Lichtman, ...
Cancer research 63 (20), 6838-6846, 2003
4702003
Multivalent effects of RGD peptides obtained by nanoparticle display
X Montet, M Funovics, K Montet-Abou, R Weissleder, L Josephson
Journal of medicinal chemistry 49 (20), 6087-6093, 2006
4612006
Differential conjugation of tat peptide to superparamagnetic nanoparticles and its effect on cellular uptake
M Zhao, MF Kircher, L Josephson, R Weissleder
Bioconjugate Chemistry 13 (4), 840-844, 2002
4532002
Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V–Cy5. 5 conjugate
V Ntziachristos, EA Schellenberger, J Ripoll, D Yessayan, E Graves, ...
Proceedings of the National Academy of Sciences 101 (33), 12294-12299, 2004
4462004
DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNA-cleaving agents
JM Perez, T O'Loughin, FJ Simeone, R Weissleder, L Josephson
Journal of the American Chemical Society 124 (12), 2856-2857, 2002
4312002
Magnetic particles for use in separations
RA Whitehead, MS Chagnon, EV Groman, L Josephson
US Patent 4,554,088, 1985
4181985
Use of magnetic nanoparticles as nanosensors to probe for molecular interactions
JM Perez, L Josephson, R Weissleder
ChemBioChem 5 (3), 261-264, 2004
3752004
Tat peptide directs enhanced clearance and hepatic permeability of magnetic nanoparticles
P Wunderbaldinger, L Josephson, R Weissleder
Bioconjugate chemistry 13 (2), 264-268, 2002
3732002
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