s k calderwood
s k calderwood
Harvard Medical School
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HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine
A Asea, SK Kraeft, EA Kurt-Jones, MA Stevenson, LB Chen, RW Finberg, ...
Nature medicine 6 (4), 435-442, 2000
Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4
A Asea, M Rehli, E Kabingu, JA Boch, O Baré, PE Auron, MA Stevenson, ...
Journal of Biological Chemistry 277 (17), 15028-15034, 2002
Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications
DR Ciocca, SK Calderwood
Cell stress & chaperones 10 (2), 86, 2005
Heat shock proteins in cancer: chaperones of tumorigenesis
SK Calderwood, MA Khaleque, DB Sawyer, DR Ciocca
Trends in biochemical sciences 31 (3), 164-172, 2006
Sequential phosphorylation by mitogen-activated protein kinase and glycogen synthase kinase 3 represses transcriptional activation by heat shock factor-1
B Chu, F Soncin, BD Price, MA Stevenson, SK Calderwood
Journal of Biological Chemistry 271 (48), 30847-30857, 1996
Extracellular heat shock proteins in cell signaling
SK Calderwood, SS Mambula, PJ Gray Jr, JR Theriault
FEBS letters 581 (19), 3689-3694, 2007
Heat shock protein 70 is secreted from tumor cells by a nonclassical pathway involving lysosomal endosomes
SS Mambula, SK Calderwood
The Journal of Immunology 177 (11), 7849-7857, 2006
The shock of aging: molecular chaperones and the heat shock response in longevity and aging–a mini-review
SK Calderwood, A Murshid, T Prince
Gerontology 55 (5), 550-558, 2009
Constitutive activation of IκB kinase α and NF-κB in prostate cancer cells is inhibited by ibuprofen
ST Palayoor, MY Youmell, SK Calderwood, CN Coleman, BD Price
Oncogene 18 (51), 7389-7394, 1999
Heat shock proteins promote cancer: it's a protection racket
SK Calderwood, J Gong
Trends in biochemical sciences 41 (4), 311-323, 2016
Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells
E Noessner, R Gastpar, V Milani, A Brandl, PJS Hutzler, MC Kuppner, ...
The journal of Immunology 169 (10), 5424-5432, 2002
The dual immunoregulatory roles of stress proteins
AG Pockley, M Muthana, SK Calderwood
Trends in biochemical sciences 33 (2), 71-79, 2008
Temperature range and selective sensitivity of tumors to hyperthermia: a critical review
JA Dickson, SK Calderwood
Annals of the New York Academy of Sciences 335 (1), 180-205, 1980
X-irradiation, phorbol esters, and H2O2 stimulate mitogen-activated protein kinase activity in NIH-3T3 cells through the formation of reactive oxygen intermediates
MA Stevenson, SS Pollock, CN Coleman, SK Calderwood
Cancer research 54 (1), 12-15, 1994
Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update
DR Ciocca, AP Arrigo, SK Calderwood
Archives of toxicology 87, 19-48, 2013
Extracellular heat shock proteins in cell signaling and immunity
SK Calderwood, SS Mambula, PJ Gray Jr
Annals of the New York Academy of Sciences 1113 (1), 28-39, 2007
Increases in Sequence Specific DNA Binding by p53 following Treatment with Chemotherapeutic and DNA Damaging Agents
RB Tishler, SK Calderwood, CN Coleman, BD Price
Cancer Research 53 (10), 2212-2216, 1993
Transcriptional repression of the prointerleukin 1β gene by heat shock factor 1
CM Cahill, WR Waterman, Y Xie, PE Auron, SK Calderwood
Journal of Biological Chemistry 271 (40), 24874-24879, 1996
Expression of heat shock proteins and heat shock protein messenger ribonucleic acid in human prostate carcinoma in vitro and in tumors in vivo
D Tang, MA Khaleque, EL Jones, JR Theriault, C Li, WH Wong, ...
Cell stress & chaperones 10 (1), 46, 2005
mTOR is essential for the proteotoxic stress response, HSF1 activation and heat shock protein synthesis
SD Chou, T Prince, J Gong, SK Calderwood
PloS one 7 (6), e39679, 2012
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