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Lorna Gilligan
Lorna Gilligan
Steroid Metabolome Analysis Core, IMSR, University of Birmingham
E-mail confirmado em bham.ac.uk
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The regulation of steroid action by sulfation and desulfation
JW Mueller, LC Gilligan, J Idkowiak, W Arlt, PA Foster
Endocrine reviews 36 (5), 526-563, 2015
2872015
Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism
W Arlt, K Lang, AJ Sitch, AS Dietz, Y Rhayem, I Bancos, A Feuchtinger, ...
JCI insight 2 (8), 2017
1662017
Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: A comprehensive review
L Schiffer, L Barnard, ES Baranowski, LC Gilligan, AE Taylor, W Arlt, ...
The Journal of steroid biochemistry and molecular biology 194, 105439, 2019
1292019
Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study
I Bancos, AE Taylor, V Chortis, AJ Sitch, C Jenkinson, CJ Davidge-Pitts, ...
The lancet Diabetes & endocrinology 8 (9), 773-781, 2020
712020
A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics
MW O’Reilly, CSJ Westgate, C Hornby, H Botfield, AE Taylor, K Markey, ...
JCI insight 4 (6), 2019
662019
Steroid metabolome analysis in disorders of adrenal steroid biosynthesis and metabolism
KH Storbeck, L Schiffer, ES Baranowski, V Chortis, A Prete, L Barnard, ...
Endocrine reviews 40 (6), 1605-1625, 2019
492019
11β-Hydroxysteroid dehydrogenase type 1 inhibition in idiopathic intracranial hypertension: a double-blind randomized controlled trial
K Markey, J Mitchell, H Botfield, RS Ottridge, T Matthews, A Krishnan, ...
Brain communications 2 (1), fcz050, 2020
362020
The utility of ultra-high performance supercritical fluid chromatography–tandem mass spectrometry (UHPSFC-MS/MS) for clinically relevant steroid analysis
KH Storbeck, L Gilligan, C Jenkinson, ES Baranowski, JL Quanson, W Arlt, ...
Journal of Chromatography B 1085, 36-41, 2018
352018
Urine steroid metabolomics as a novel tool for detection of recurrent adrenocortical carcinoma
V Chortis, I Bancos, T Nijman, LC Gilligan, AE Taylor, CL Ronchi, ...
The Journal of Clinical Endocrinology & Metabolism 105 (3), e307-e318, 2020
312020
Estrone sulfate transport and steroid sulfatase activity in colorectal cancer: implications for hormone replacement therapy
LC Gilligan, A Gondal, V Tang, MT Hussain, A Arvaniti, AM Hewitt, ...
Frontiers in Pharmacology 8, 103, 2017
252017
Estrogen activation by steroid sulfatase increases colorectal cancer proliferation via GPER
LC Gilligan, HP Rahman, AM Hewitt, AJ Sitch, A Gondal, A Arvaniti, ...
The Journal of Clinical Endocrinology & Metabolism 102 (12), 4435-4447, 2017
202017
11βHSD1 inhibition with AZD4017 improves lipid profiles and lean muscle mass in idiopathic intracranial hypertension
RS Hardy, H Botfield, K Markey, JL Mitchell, Z Alimajstorovic, ...
The Journal of Clinical Endocrinology & Metabolism 106 (1), 174-187, 2021
182021
Mapping the steroid response to major trauma from injury to recovery: a prospective cohort study
MA Foster, AE Taylor, NE Hill, C Bentley, J Bishop, LC Gilligan, ...
The Journal of Clinical Endocrinology & Metabolism 105 (3), 925-937, 2020
172020
Accurate non‐invasive diagnosis and staging of non‐alcoholic fatty liver disease using the urinary steroid metabolome
A Moolla, J de Boer, D Pavlov, A Amin, A Taylor, L Gilligan, B Hughes, ...
Alimentary pharmacology & therapeutics 51 (11), 1188-1197, 2020
122020
Residual Adrenal Function in Autoimmune Addison’s Disease—Effect of Dual Therapy With Rituximab and Depot Tetracosactide
C Napier, EH Gan, AL Mitchell, LC Gilligan, DA Rees, C Moran, ...
The Journal of Clinical Endocrinology & Metabolism 105 (4), e1250-e1259, 2020
122020
AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells
N Nikolaou, LL Gathercole, L Kirkwood, JE Dunford, BA Hughes, ...
The Journal of steroid biochemistry and molecular biology 189, 218-227, 2019
122019
Insights from the genetic characterization of central precocious puberty associated with multiple anomalies
APM Canton, ACV Krepischi, LR Montenegro, S Costa, C Rosenberg, ...
Human Reproduction 36 (2), 506-518, 2021
82021
The A-ring reduction of 11-ketotestosterone is efficiently catalysed by AKR1D1 and SRD5A2 but not SRD5A1
L Barnard, N Nikolaou, C Louw, L Schiffer, H Gibson, LC Gilligan, ...
The Journal of steroid biochemistry and molecular biology 202, 105724, 2020
82020
Cardiometabolic disease burden and steroid excretion in benign adrenal tumors: a cross-sectional multicenter study
A Prete, A Subramanian, I Bancos, V Chortis, S Tsagarakis, K Lang, ...
Annals of internal medicine 175 (3), 325-334, 2022
62022
Altered cortisol metabolism in individuals with HNF1A‐MODY
A Juszczak, LC Gilligan, BA Hughes, ZK Hassan‐Smith, MI McCarthy, ...
Clinical Endocrinology 93 (3), 269-279, 2020
42020
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Artigos 1–20