The microglial innate immune receptor TREM2 is required for synapse elimination and normal brain connectivity F Filipello, R Morini, I Corradini, V Zerbi, A Canzi, B Michalski, M Erreni, ... Immunity 48 (5), 979-991. e8, 2018 | 517 | 2018 |
Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia N Scott‐Hewitt, F Perrucci, R Morini, M Erreni, M Mahoney, A Witkowska, ... The EMBO journal 39 (16), e105380, 2020 | 259 | 2020 |
TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis F Cignarella, F Filipello, B Bollman, C Cantoni, A Locca, R Mikesell, ... Acta neuropathologica 140, 513-534, 2020 | 234 | 2020 |
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk Y Deming, F Filipello, F Cignarella, C Cantoni, S Hsu, R Mikesell, Z Li, ... Science translational medicine 11 (505), eaau2291, 2019 | 210 | 2019 |
TBC1D24, an ARF6-interacting protein, is mutated in familial infantile myoclonic epilepsy A Falace, F Filipello, V La Padula, N Vanni, F Madia, DDP Tonelli, ... The American Journal of Human Genetics 87 (3), 365-370, 2010 | 170 | 2010 |
Early exposure to a high-fat diet impacts on hippocampal plasticity: implication of microglia-derived exosome-like extracellular vesicles A Vinuesa, M Bentivegna, G Calfa, F Filipello, C Pomilio, ... Molecular neurobiology 56, 5075-5094, 2019 | 70 | 2019 |
Soluble TREM2: Innocent bystander or active player in neurological diseases? F Filipello, C Goldsbury, SF You, A Locca, CM Karch, L Piccio Neurobiology of disease 165, 105630, 2022 | 53 | 2022 |
Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1‐integrin G Fossati, D Pozzi, A Canzi, F Mirabella, S Valentino, R Morini, ... The EMBO journal 38 (1), e99529, 2019 | 53 | 2019 |
Amyloid-β 1–24 C-terminal truncated fragment promotes amyloid-β 1–42 aggregate formation in the healthy brain S Mazzitelli, F Filipello, M Rasile, E Lauranzano, C Starvaggi-Cucuzza, ... Acta neuropathologica communications 4, 1-19, 2016 | 34 | 2016 |
Liver X receptor agonist GW3965 regulates synaptic function upon amyloid beta exposure in hippocampal neurons C Báez-Becerra, F Filipello, A Sandoval-Hernández, H Arboleda, ... Neurotoxicity research 33, 569-579, 2018 | 30 | 2018 |
Ectonucleotidase activity and immunosuppression in astrocyte-CD4 T cell bidirectional signaling F Filipello, D Pozzi, M Proietti, A Romagnani, S Mazzitelli, M Matteoli, ... Oncotarget 7 (5), 5143, 2016 | 20 | 2016 |
Strategies and tools for studying microglial-mediated synapse elimination and refinement R Morini, M Bizzotto, F Perrucci, F Filipello, M Matteoli Frontiers in Immunology 12, 640937, 2021 | 14 | 2021 |
Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation F Filipello, SF You, FS Mirfakhar, S Mahali, B Bollman, M Acquarone, ... Acta neuropathologica 145 (6), 749-772, 2023 | 13 | 2023 |
Trem2 expression in microglia is required to maintain normal neuronal bioenergetics during development E Tagliatti, G Desiato, S Mancinelli, M Bizzotto, MC Gagliani, E Faggiani, ... Immunity 57 (1), 86-105. e9, 2024 | 4 | 2024 |
MS4A4A modifies the risk of Alzheimer disease by regulating lipid metabolism and immune response in a unique microglia state SF You, L Brase, F Filipello, AK Iyer, J Del-Aguila, J He, RDO Albanus, ... medRxiv, 2023 | 4 | 2023 |
Loss of interleukin 1 signaling causes impairment of microglia-mediated synapse elimination and autistic-like behaviour in mice A Borreca, C Mantovani, G Desiato, I Corradini, F Filipello, CA Elia, ... Brain, Behavior, and Immunity 117, 493-509, 2024 | 2 | 2024 |
Protective genetic variants in the MS4A gene cluster modulate microglial activity: Imaging and biomarker correlates of genetic variants protective against AD Y Deming, F Filipello, F Cignarella, M Suárez‐Calvet, ... Alzheimer's & Dementia 16, e039431, 2020 | 2 | 2020 |
Extracellular vesicles released by microglia and macrophages carry endocannabinoids which foster oligodendrocyte differentiation M Lombardi, F Scaroni, M Gabrielli, S Raffaele, E Bonfanti, F Filipello, ... Frontiers in Immunology 15, 1331210, 2024 | | 2024 |
Transient Receptor Potential Vanilloid 4-Dependent Microglial Function in Myelin Injury and Repair JP Holloman, SH Dimas, AS Archambault, F Filipello, L Du, J Feng, ... International journal of molecular sciences 24 (23), 17097, 2023 | | 2023 |
Interplay Between Microglial Receptor TREM2 and Maternal Immune Challenges in Schizophrenia M Bizzotto, SF You, E Faggiani, M Tamborini, F Perrucci, R Morini, ... GLIA 71, E907-E908, 2023 | | 2023 |