Jon Boyle
Jon Boyle
Department of Biological Sciences, University of Pittsburgh
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Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue
JPJ Saeij, S Coller, JP Boyle, ME Jerome, MW White, JC Boothroyd
Nature 445 (7125), 324-327, 2007
Polymorphic secreted kinases are key virulence factors in toxoplasmosis
JPJ Saeij, JP Boyle, S Coller, S Taylor, LD Sibley, ET Brooke-Powell, ...
Science 314 (5806), 1780-1783, 2006
Differences among the three major strains of Toxoplasma gondii and their specific interactions with the infected host
JPJ Saeij, JP Boyle, JC Boothroyd
Trends in parasitology 21 (10), 476-481, 2005
Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence
ML Reese, GM Zeiner, JPJ Saeij, JC Boothroyd, JP Boyle
Proceedings of the National Academy of Sciences 108 (23), 9625-9630, 2011
Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii
A Khan, S Taylor, C Su, AJ Mackey, J Boyle, R Cole, D Glover, K Tang, ...
Nucleic acids research 33 (9), 2980-2992, 2005
Bioluminescence Imaging of Toxoplasma gondii Infection in Living Mice Reveals Dramatic Differences between Strains
JPJ Saeij, JP Boyle, ME Grigg, G Arrizabalaga, JC Boothroyd
Infection and immunity 73 (2), 695-702, 2005
Using RNA interference to manipulate endogenous gene expression in Schistosoma mansoni sporocysts
JP Boyle, XJ Wu, CB Shoemaker, TP Yoshino
Molecular and biochemical parasitology 128 (2), 205-215, 2003
Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole
A Khaminets, JP Hunn, S Könen‐Waisman, YO Zhao, D Preukschat, ...
Cellular microbiology 12 (7), 939-961, 2010
Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes
H Lorenzi, A Khan, MS Behnke, S Namasivayam, LS Swapna, ...
Nature communications 7 (1), 1-13, 2016
Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii
JP Boyle, B Rajasekar, JPJ Saeij, JW Ajioka, M Berriman, I Paulsen, ...
Proceedings of the National Academy of Sciences 103 (27), 10514-10519, 2006
Description of the Transcriptomes of Immune Response-Activated Hemocytes from the Mosquito Vectors Aedes aegypti and Armigeres subalbatus
LC Bartholomay, WL Cho, TA Rocheleau, JP Boyle, ET Beck, JF Fuchs, ...
Infection and immunity 72 (7), 4114-4126, 2004
Toxoplasma Effector MAF1 Mediates Recruitment of Host Mitochondria and Impacts the Host Response
L Pernas, Y Adomako-Ankomah, AJ Shastri, SE Ewald, M Treeck, ...
PLoS biology 12 (4), e1001845, 2014
Age‐associated mortality in immune challenged mosquitoes (Aedes aegypti) correlates with a decrease in haemocyte numbers
JF Hillyer, SL Schmidt, JF Fuchs, JP Boyle, BM Christensen
Cellular microbiology 7 (1), 39-51, 2005
A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance
CA McConkey, E Delorme-Axford, CA Nickerson, KS Kim, Y Sadovsky, ...
Science advances 2 (3), e1501462, 2016
Human trophoblasts confer resistance to viruses implicated in perinatal infection
A Bayer, E Delorme-Axford, C Sleigher, TK Frey, DW Trobaugh, ...
American journal of obstetrics and gynecology 212 (1), 71. e1-71. e8, 2015
Integrated Bioinformatic and Targeted Deletion Analyses of the SRS Gene Superfamily Identify SRS29C as a Negative Regulator of Toxoplasma Virulence
JD Wasmuth, V Pszenny, S Haile, EM Jansen, AT Gast, A Sher, JP Boyle, ...
MBio 3 (6), e00321-12, 2012
Toxoplasma gondii: inconsistent dissemination patterns following oral infection in mice
JP Boyle, JPJ Saeij, JC Boothroyd
Experimental parasitology 116 (3), 302-305, 2007
Location of the CD8 T Cell Epitope within the Antigenic Precursor Determines Immunogenicity and Protection against the Toxoplasma gondii Parasite
V Feliu, V Vasseur, HS Grover, HH Chu, MJ Brown, J Wang, JP Boyle, ...
PLoS pathogens 9 (6), e1003449, 2013
Whole genome sequencing of a natural recombinant Toxoplasma gondii strain reveals chromosome sorting and local allelic variants
IL Bontell, N Hall, KE Ashelford, JP Dubey, JP Boyle, J Lindh, JE Smith
Genome biology 10 (5), 1-17, 2009
Hammondia hammondi, an avirulent relative of Toxoplasma gondii, has functional orthologs of known T. gondii virulence genes
KA Walzer, Y Adomako-Ankomah, RA Dam, DC Herrmann, G Schares, ...
Proceedings of the National Academy of Sciences 110 (18), 7446-7451, 2013
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