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Newton G. Castro
Newton G. Castro
E-mail confirmado em farmaco.ufrj.br
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Properties of neuronal nicotinic acetylcholine receptors: pharmacological characterization and modulation of synaptic function
EX Albuquerque, M Alkondon, EFR Pereira, NG Castro, A Schrattenholz, ...
Journal of Pharmacology and Experimental Therapeutics 280 (3), 1117-1136, 1997
5661997
alpha-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability
NG Castro, EX Albuquerque
Biophysical journal 68 (2), 516-524, 1995
3361995
Astrocyte-induced synaptogenesis is mediated by transforming growth factor β signaling through modulation of D-serine levels in cerebral cortex neurons
LP Diniz, JC Almeida, V Tortelli, CV Lopes, P Setti-Perdigão, J Stipursky, ...
Journal of Biological Chemistry 287 (49), 41432-41445, 2012
2452012
Nicotinic receptor function in the mammalian central nervous system.
EX Albuquerque, EF Pereira, NG Castro, M Alkondon, S Reinhardt, ...
Annals of the New York Academy of Sciences 757, 48-72, 1995
2171995
Altered oxygen metabolism associated to neurogenesis of induced pluripotent stem cells derived from a schizophrenic patient
B da Silveira Paulsen, R de Moraes Maciel, A Galina, MS Da Silveira, ...
Cell transplantation 21 (7), 1547-1559, 2012
1662012
Choline and acetylcholine have similar kinetic properties of activation and desensitization on the α7 nicotinic receptors in rat hippocampal neurons
A Mike, NG Castro, EX Albuquerque
Brain research 882 (1-2), 155-168, 2000
1652000
Colchicine inhibits cationic dye uptake induced by ATP in P2X2 and P2X7 receptor‐expressing cells: implications for its therapeutic action
C Marques‐da‐Silva, MM Chaves, NG Castro, R Coutinho‐Silva, ...
British journal of pharmacology 163 (5), 912-926, 2011
1612011
Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice
CP Figueiredo, FGQ Barros-Aragão, RLS Neris, PS Frost, C Soares, ...
Nature communications 10 (1), 3890, 2019
1512019
Design, Synthesis, and Pharmacological Profile of Novel Fused Pyrazolo[4,3-d]pyridine and Pyrazolo[3,4-b][1,8]naphthyridine Isosteres:  A New Class of Potent …
EJ Barreiro, CA Camara, H Verli, L Brazil-Más, NG Castro, WM Cintra, ...
Journal of medicinal chemistry 46 (7), 1144-1152, 2003
1432003
Synthesis and preliminary pharmacological evaluation of new (±) 1, 4-naphthoquinones structurally related to lapachol
AJM da Silva, CD Buarque, FV Brito, L Aurelian, LF Macedo, LH Malkas, ...
Bioorganic & medicinal chemistry 10 (8), 2731-2738, 2002
1132002
Astrocyte transforming growth factor beta 1 promotes inhibitory synapse formation via CaM kinase II signaling
LP Diniz, V Tortelli, MN Garcia, APB Araújo, HM Melo, GS Seixas da Silva, ...
Glia 62 (12), 1917-1931, 2014
1112014
Cardanol-derived AChE inhibitors: Towards the development of dual binding derivatives for Alzheimer's disease
LFN Lemes, G de Andrade Ramos, AS De Oliveira, FMR Da Silva, ...
European Journal of Medicinal Chemistry 108, 687-700, 2016
992016
Brief-lifetime, fast-inactivating ion channels account for the α-bungarotoxin-sensitive nicotinic response in hippocampal neurons
NG Castro, EX Albuquerque
Neuroscience letters 164 (1-2), 137-140, 1993
941993
Design, synthesis and evaluation of novel feruloyl-donepezil hybrids as potential multitarget drugs for the treatment of Alzheimer's disease
KST Dias, CT de Paula, T Dos Santos, INO Souza, MS Boni, ...
European journal of medicinal chemistry 130, 440-457, 2017
862017
New selective acetylcholinesterase inhibitors designed from natural piperidine alkaloids
C Viegas Jr, VS Bolzani, LSB Pimentel, NG Castro, RF Cabral, RS Costa, ...
Bioorganic & medicinal chemistry 13 (13), 4184-4190, 2005
852005
Direct inhibition of the N‐methyl‐D‐aspartate receptor channel by dopamine and (+)‐SKF38393
NG Castro, MCF De Mello, FG De Mello, Y Aracava
British journal of pharmacology 126 (8), 1847-1855, 1999
821999
Geissospermum vellosii stembark: anticholinesterase activity and improvement of scopolamine-induced memory deficits
JA Lima, RS Costa, RA Epifânio, NG Castro, MS Rocha, AC Pinto
Pharmacology biochemistry and behavior 92 (3), 508-513, 2009
702009
New potential AChE inhibitor candidates
AAN De Paula, JBL Martins, ML Dos Santos, LC Nascente, LAS Romeiro, ...
European Journal of Medicinal Chemistry 44 (9), 3754-3759, 2009
642009
A novel agonist binding site on nicotinic acetylcholine receptors
EFR Pereira, M Alkondon, T Tano, NG Castro, MM Fróes-Ferra¯ o, ...
Journal of receptor research 13 (1-4), 413-436, 1993
621993
Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer …
FPD Viegas, M de Freitas Silva, MD da Rocha, MR Castelli, MM Riquiel, ...
European Journal of Medicinal Chemistry 147, 48-65, 2018
572018
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