| Cathepsin B Activity Regulation: heparin-like glycosaminoglycans protect human cathepsin b from alkaline ph-induced inactivation PC Almeida, IL Nantes, JR Chagas, CCA Rizzi, A Faljoni-Alario, ... Journal of Biological Chemistry 276 (2), 944-951, 2001 | 235 | 2001 |
| Tellurium-based cysteine protease inhibitors: evaluation of novel organotellurium (IV) compounds as inhibitors of human cathepsin B RLOR Cunha, ME Urano, JR Chagas, PC Almeida, C Bincoletto, ... Bioorganic & medicinal chemistry letters 15 (3), 755-760, 2005 | 148 | 2005 |
| Increase in kinins on post-exercise hypotension in normotensive and hypertensive volunteers MR Moraes, RFP Bacurau, JDS Ramalho, FCG Reis, DE Casarini, ... Walter de Gruyter 388 (5), 533-540, 2007 | 146 | 2007 |
| Intramolecularly quenched fluorogenic tetrapeptide substrates for tissue and plasma kallikreins JR Chagas, L Juliano, ES Prado Analytical Biochemistry 192 (2), 419-425, 1991 | 146 | 1991 |
| Purification and characterization of an alkaline serine endopeptidase from a feather-degrading Xanthomonas maltophilia strain CH De Toni, MF Richter, JR Chagas, JAP Henriques, C Termignoni Canadian Journal of Microbiology 48 (4), 342-348, 2002 | 121 | 2002 |
| Heparan sulfate modulates kinin release by Trypanosoma cruzi through the activity of cruzipain APCA Lima, PC Almeida, ILS Tersariol, V Schmitz, AH Schmaier, ... Journal of Biological Chemistry 277 (8), 5875-5881, 2002 | 98 | 2002 |
| Substrate specificity of human kallikrein 2 (hK2) as determined by phage display technology SM Cloutier, JR Chagas, JP Mach, CM Gygi, HJ Leisinger, D Deperthes European journal of biochemistry 269 (11), 2747-2754, 2002 | 87 | 2002 |
| Determinants of the unusual cleavage specificity of lysyl-bradykinin-releasing kallikreins JR Chagas, FCV Portaro, IY Hirata, PC Almeida, MA Juliano, L Juliano, ... Biochemical Journal 306 (1), 63-69, 1995 | 78 | 1995 |
| Enzymatic profiling of human kallikrein 14 using phage-display substrate technology LM Felber, CA Borgono, SM Cloutier, C Kündig, T Kishi, JR Chagas, ... Walter de Gruyter 386 (3), 291-298, 2005 | 77 | 2005 |
| Purification and partial characterization of two phospholipases A2 from Bothrops leucurus (white-tailed-jararaca) snake venom DA Higuchi, CMV Barbosa, C Bincoletto, JR Chagas, A Magalhaes, ... Biochimie 89 (3), 319-328, 2007 | 73 | 2007 |
| Cysteine proteinase activity regulation: a possible role of heparin and heparin-like glycosaminoglycans PC Almeida, IL Nantes, CCA Rizzi, WAS Judice, JR Chagas, L Juliano, ... Journal of Biological Chemistry 274 (43), 30433-30438, 1999 | 68 | 1999 |
| Inhibition of trypanosomal cysteine proteinases by their propeptides G Lalmanach, F Lecaille, JR Chagas, E Authié, J Scharfstein, MA Juliano, ... Journal of Biological Chemistry 273 (39), 25112-25116, 1998 | 63 | 1998 |
| Validation of housekeeping genes in the brains of rats submitted to chronic intermittent hypoxia, a sleep apnea model GS Julian, RW de Oliveira, JC Perry, S Tufik, JR Chagas PloS one 9 (10), e109902, 2014 | 60 | 2014 |
| Intramolecularly quenched fluorogenic peptide substrates for human renin MCF Oliveira, IY Hirata, JR Chagas, P Boschcov, RAS Gomes, ... Analytical Biochemistry 203 (1), 39-46, 1992 | 58 | 1992 |
| A comparison of the enzymatic properties of the major cysteine proteinases from Trypanosoma congolense and Trypanosoma cruzi JR Chagas, E Authié, C Serveau, G Lalmanach, L Juliano, F Gauthier Molecular and biochemical parasitology 88 (1-2), 85-94, 1997 | 57 | 1997 |
| The blood-brain barrier breakdown during acute phase of the pilocarpine model of epilepsy is dynamic and time-dependent NF Mendes, AP Pansani, ERF Carmanhães, P Tange, JV Meireles, ... Frontiers in neurology 10, 382, 2019 | 56 | 2019 |
| Development of recombinant inhibitors specific to human kallikrein 2 using phage‐display selected substrates SM Cloutier, C Kündig, LM Felber, OM Fattah, JR Chagas, CM Gygi, ... European journal of biochemistry 271 (3), 607-613, 2004 | 55 | 2004 |
| ACE Activity Is Modulated by Kinin B2 Receptor RA Sabatini, PB Guimaraes, L Fernandes, FCG Reis, PA Bersanetti, ... Hypertension 51 (3), 689-695, 2008 | 51 | 2008 |
| Inhibition of cathepsin B by its propeptide: use of overlapping peptides to identify a critical segment JR Chagas, M Ferrer-Di Martino, F Gauthier, G Lalmanach FEBS letters 392 (3), 233-236, 1996 | 51 | 1996 |
| A selective assay for endooligopeptidase A based on the cleavage of fluorogenic substrate structurally related to enkephalin L Juliano, JR Chagas, IY Hirata, E Carmona, M Sucupira, ES Oliveira, ... Biochemical and biophysical research communications 173 (2), 647-652, 1990 | 50 | 1990 |
