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Mourad Toporsian
Mourad Toporsian
Brigham & Women's Hospital, Harvard Medical School
E-mail confirmado em partners.org
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Soluble endoglin contributes to the pathogenesis of preeclampsia
S Venkatesha, M Toporsian, C Lam, J Hanai, T Mammoto, YM Kim, ...
Nature medicine 12 (6), 642-649, 2006
24022006
A role for endoglin in coupling eNOS activity and regulating vascular tone revealed in hereditary hemorrhagic telangiectasia
M Toporsian, R Gros, MG Kabir, S Vera, K Govindaraju, DH Eidelman, ...
Circulation research 96 (6), 684-692, 2005
3352005
Reduced angiogenic responses in adult Endoglin heterozygous mice
M Jerkic, A Rodríguez-Barbero, M Prieto, M Toporsian, M Pericacho, ...
Cardiovascular research 69 (4), 845-854, 2006
1502006
Hypoxia induces a functionally significant and translationally efficient neuronal NO synthase mRNA variant
ME Ward, M Toporsian, JA Scott, H Teoh, V Govindaraju, A Quan, ...
The Journal of clinical investigation 115 (11), 3128-3139, 2005
1362005
Downregulation of endothelial nitric oxide synthase in rat aorta after prolonged hypoxia in vivo
M Toporsian, K Govindaraju, M Nagi, D Eidelman, G Thibault, ME Ward
Circulation research 86 (6), 671-675, 2000
1092000
Cerebral vascular abnormalities in a murine model of hereditary hemorrhagic telangiectasia
J Satomi, RJ Mount, M Toporsian, AD Paterson, MC Wallace, RV Harrison, ...
Stroke 34 (3), 783-789, 2003
982003
Release of cellular tension signals self-restorative ventral lamellipodia to heal barrier micro-wounds
R Martinelli, M Kamei, PT Sage, R Massol, L Varghese, T Sciuto, ...
Journal of Cell Biology 201 (3), 449-465, 2013
862013
Spontaneous adult-onset pulmonary arterial hypertension attributable to increased endothelial oxidative stress in a murine model of hereditary hemorrhagic telangiectasia
M Toporsian, M Jerkic, YQ Zhou, MG Kabir, LX Yu, BAS McIntyre, A Davis, ...
Arteriosclerosis, thrombosis, and vascular biology 30 (3), 509-517, 2010
592010
Circulating anti-angiogenic factors during hypertensive pregnancy and increased risk of respiratory distress syndrome in preterm neonates
A Wang, AM Holston, KF Yu, J Zhang, M Toporsian, SA Karumanchi, ...
The Journal of Maternal-Fetal & Neonatal Medicine 25 (8), 1447-1452, 2012
472012
Age-dependent endothelial nitric oxide synthase uncoupling in pulmonary arteries of endoglin heterozygous mice
J Belik, M Jerkic, BAS McIntyre, J Pan, J Leen, LX Yu, RM Henkelman, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 297 (6 …, 2009
382009
Hyporeactivity of rat diaphragmatic arterioles after exposure to hypoxia in vivo: role of the endothelium
M Toporsian, ME Ward
American journal of respiratory and critical care medicine 156 (5), 1572-1578, 1997
311997
Novel protein interactions with endoglin and activin receptor-like kinase 1: potential role in vascular networks
G Xu, M Barrios-Rodiles, M Jerkic, AL Turinsky, R Nadon, S Vera, ...
Molecular & Cellular Proteomics 13 (2), 489-502, 2014
262014
A disorder-related variant (E420K) of a PP2A-regulatory subunit (PPP2R5D) causes constitutively active AKT-mTOR signaling and uncoordinated cell growth
CM Papke, KA Smolen, MR Swingle, L Cressey, RA Heng, M Toporsian, ...
Journal of Biological Chemistry 296, 2021
232021
Capillary electrophoresis analysis of nitrite and nitrate in sub-microliter quantities of airway surface liquid
K Govindaraju, M Toporsian, ME Ward, DK Lloyd, EA Cowley, ...
Journal of Chromatography B: Biomedical Sciences and Applications 762 (2 …, 2001
192001
Use of compounds that bind soluble endoglin and SFLT-1 for the treatment of pregnancy related hypertensive disorders
SA Karumanchi, VP Sukhatme, M Toporsian, MV Letarte
US Patent 7,740,849, 2010
152010
Enhancement of aortic contractility by endothelin following prolonged hypoxia in vivo
ME Zacour, M Toporsian, G Auer, P Cernacek, ME Ward
Pulmonary Pharmacology & Therapeutics 11 (2-3), 197-199, 1998
151998
Methods of Diagnosing and Treating Complications of Pregnancy
AS Karumanchi, VP Sukhatme, M Toporsian, MV Letarte
US Patent App. 12/227,658, 2009
142009
Neuronal nitric oxide synthase expression in rat aortic smooth muscle following in-vivo hypoxia
M Toporsian, V Govindaraju, A Giaid, ME Ward
CIRCULATION 98 (17), 386-387, 1998
11998
Methods of diagnosing and treating complications of pregnancy
SA Karumanchi, VP Sukhatme, M Toporsian, MV Letarte
US Patent App. 15/279,102, 2017
2017
Soluble endoglin and uses thereof
M Toporsian
US Patent 8,795,663, 2014
2014
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Artigos 1–20