Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation RM Stone, SJ Mandrekar, BL Sanford, K Laumann, S Geyer, ... New England Journal of Medicine 377 (5), 454-464, 2017 | 2292 | 2017 |
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B M Fabbri, R Garzon, A Cimmino, Z Liu, N Zanesi, E Callegari, S Liu, ... Proceedings of the National Academy of Sciences 104 (40), 15805-15810, 2007 | 2038 | 2007 |
Targeting microRNAs in cancer: rationale, strategies and challenges R Garzon, G Marcucci, CM Croce Nature reviews Drug discovery 9 (10), 775-789, 2010 | 1860 | 2010 |
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia KG Roberts, Y Li, D Payne-Turner, RC Harvey, YL Yang, D Pei, ... New England journal of medicine 371 (11), 1005-1015, 2014 | 1538 | 2014 |
IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia … G Marcucci, K Maharry, YZ Wu, MD Radmacher, K Mrózek, D Margeson, ... Journal of clinical oncology 28 (14), 2348-2355, 2010 | 991 | 2010 |
R-2HG exhibits anti-tumor activity by targeting FTO/m6A/MYC/CEBPA signaling R Su, L Dong, C Li, S Nachtergaele, M Wunderlich, Y Qing, X Deng, ... Cell 172 (1), 90-105. e23, 2018 | 945 | 2018 |
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly … R Garzon, S Liu, M Fabbri, Z Liu, CEA Heaphy, E Callegari, S Schwind, ... Blood, The Journal of the American Society of Hematology 113 (25), 6411-6418, 2009 | 932 | 2009 |
METTL14 inhibits hematopoietic stem/progenitor differentiation and promotes leukemogenesis via mRNA m6A modification H Weng, H Huang, H Wu, X Qin, BS Zhao, L Dong, H Shi, J Skibbe, ... Cell stem cell 22 (2), 191-205. e9, 2018 | 865 | 2018 |
Adverse Prognostic Significance of KIT Mutations in Adult Acute Myeloid Leukemia With inv(16) and t(8;21): A Cancer and Leukemia Group B Study P Paschka, G Marcucci, AS Ruppert, K Mrózek, H Chen, RA Kittles, ... Journal of Clinical Oncology 24 (24), 3904-3911, 2006 | 862 | 2006 |
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia R Garzon, S Volinia, CG Liu, C Fernandez-Cymering, T Palumbo, ... Blood, The Journal of the American Society of Hematology 111 (6), 3183-3189, 2008 | 835 | 2008 |
Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular … K Mrózek, G Marcucci, P Paschka, SP Whitman, CD Bloomfield Blood 109 (2), 431-448, 2007 | 813 | 2007 |
Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications G Marcucci, T Haferlach, H Döhner Journal of Clinical Oncology 29 (5), 475-486, 2011 | 781 | 2011 |
Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur, J Cortes, ... Cancer discovery 4 (3), 362-375, 2014 | 750 | 2014 |
miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts AM Eiring, JG Harb, P Neviani, C Garton, JJ Oaks, R Spizzo, S Liu, ... Cell 140 (5), 652-665, 2010 | 708 | 2010 |
Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine W Blum, R Garzon, RB Klisovic, S Schwind, A Walker, S Geyer, S Liu, ... Proceedings of the National Academy of Sciences 107 (16), 7473-7478, 2010 | 604 | 2010 |
The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein P Neviani, R Santhanam, R Trotta, M Notari, BW Blaser, S Liu, H Mao, ... Cancer cell 8 (5), 355-368, 2005 | 601 | 2005 |
MicroRNA fingerprints during human megakaryocytopoiesis R Garzon, F Pichiorri, T Palumbo, R Iuliano, A Cimmino, R Aqeilan, ... Proceedings of the National Academy of Sciences 103 (13), 5078-5083, 2006 | 600 | 2006 |
MicroRNA 29b functions in acute myeloid leukemia R Garzon, CEA Heaphy, V Havelange, M Fabbri, S Volinia, T Tsao, ... Blood, The Journal of the American Society of Hematology 114 (26), 5331-5341, 2009 | 563 | 2009 |
MicroRNA expression in cytogenetically normal acute myeloid leukemia G Marcucci, MD Radmacher, K Maharry, K Mrózek, AS Ruppert, ... New England Journal of Medicine 358 (18), 1919-1928, 2008 | 543 | 2008 |
Targeting FTO suppresses cancer stem cell maintenance and immune evasion R Su, L Dong, Y Li, M Gao, L Han, M Wunderlich, X Deng, H Li, Y Huang, ... Cancer cell 38 (1), 79-96. e11, 2020 | 541 | 2020 |