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Markus Sikkel
Markus Sikkel
Centre for Cardiovascular Innovation at UBC
E-mail confirmado em uvic.ca - Página inicial
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High Levels of Circulating Epinephrine Trigger Apical Cardiodepression in a β2-Adrenergic Receptor/Gi–Dependent Manner: A New Model of Takotsubo …
H Paur, PT Wright, MB Sikkel, MH Tranter, C Mansfield, P O'gara, ...
Circulation 126 (6), 697-706, 2012
7952012
Trends in mortality from ischemic heart disease and cerebrovascular disease in Europe: 1980 to 2009
A Hartley, DC Marshall, JD Salciccioli, MB Sikkel, M Maruthappu, ...
Circulation 133 (20), 1916-1926, 2016
3192016
Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling
PT Wright, VO Nikolaev, T O'Hara, I Diakonov, A Bhargava, S Tokar, ...
Journal of molecular and cellular cardiology 67, 38-48, 2014
1272014
Myocardial MiR-30 downregulation triggered by doxorubicin drives alterations in β-adrenergic signaling and enhances apoptosis
L Roca-Alonso, L Castellano, A Mills, AF Dabrowska, MB Sikkel, ...
Cell death & disease 6 (5), e1754-e1754, 2015
1232015
Respiratory syncytial virus persistence in chronic obstructive pulmonary disease
MB Sikkel, JK Quint, P Mallia, JA Wedzicha, SL Johnston
The Pediatric infectious disease journal 27 (10), S63-S70, 2008
1202008
Plasticity of Surface Structures and β2-Adrenergic Receptor Localization in Failing Ventricular Cardiomyocytes During Recovery From Heart Failure
AR Lyon, VO Nikolaev, M Miragoli, MB Sikkel, H Paur, L Benard, JS Hulot, ...
Circulation: Heart Failure 5 (3), 357-365, 2012
1172012
Hierarchical statistical techniques are necessary to draw reliable conclusions from analysis of isolated cardiomyocyte studies
MB Sikkel, DP Francis, J Howard, F Gordon, C Rowlands, NS Peters, ...
Cardiovascular research 113 (14), 1743-1752, 2017
1132017
Microdomain-specific modulation of L-type calcium channels leads to triggered ventricular arrhythmia in heart failure
JL Sanchez-Alonso, A Bhargava, T O’Hara, AV Glukhov, ...
Circulation research 119 (8), 944-955, 2016
1132016
The mechanism of flecainide action in CPVT does not involve a direct effect on RyR2
ML Bannister, NL Thomas, MB Sikkel, S Mukherjee, C Maxwell, ...
Circulation research 116 (8), 1324-1335, 2015
952015
High-speed 2D and 3D fluorescence microscopy of cardiac myocytes
S Kumar, D Wilding, MB Sikkel, AR Lyon, KT MacLeod, C Dunsby
Optics express 19 (15), 13839-13847, 2011
932011
Direct evidence for microdomain-specific localization and remodeling of functional L-type calcium channels in rat and human atrial myocytes
AV Glukhov, M Balycheva, JL Sanchez-Alonso, Z Ilkan, A Alvarez-Laviada, ...
Circulation 132 (25), 2372-2384, 2015
902015
Flecainide reduces Ca2+ spark and wave frequency via inhibition of the sarcolemmal sodium current
MB Sikkel, TP Collins, C Rowlands, M Shah, P O'Gara, AJ Williams, ...
Cardiovascular research 98 (2), 286-296, 2013
862013
Myosin regulatory light chain (RLC) phosphorylation change as a modulator of cardiac muscle contraction in disease
C Toepfer, V Caorsi, T Kampourakis, MB Sikkel, T West, JC Leung, ...
Biophysical Journal 104 (2), 309a-310a, 2013
822013
Investigation of cardiac fibroblasts using myocardial slices
F Perbellini, SA Watson, M Scigliano, S Alayoubi, S Tkach, I Bardi, ...
Cardiovascular research 114 (1), 77-89, 2018
682018
T-tubule remodelling disturbs localized β2-adrenergic signalling in rat ventricular myocytes during the progression of heart failure
S Schobesberger, P Wright, S Tokar, A Bhargava, C Mansfield, ...
Cardiovascular research 113 (7), 770-782, 2017
612017
Visualizing localized reentry with ultra–high density mapping in iatrogenic atrial tachycardia: beware pseudo-reentry
V Luther, M Sikkel, N Bennett, F Guerrero, K Leong, N Qureshi, FS Ng, ...
Circulation: Arrhythmia and Electrophysiology 10 (4), e004724, 2017
612017
Efficacy and safety of same-day discharge for atrial fibrillation ablation
MW Deyell, RA Leather, L Macle, J Forman, P Khairy, R Zhang, L Ding, ...
Clinical Electrophysiology 6 (6), 609-619, 2020
592020
Microtubule-dependent mitochondria alignment regulates calcium release in response to nanomechanical stimulus in heart myocytes
M Miragoli, JL Sanchez-Alonso, A Bhargava, PT Wright, M Sikkel, ...
Cell reports 14 (1), 140-151, 2016
582016
SERCA2a gene therapy in heart failure: an anti‐arrhythmic positive inotrope
MB Sikkel, C Hayward, KT MacLeod, SE Harding, AR Lyon
British journal of pharmacology 171 (1), 38-54, 2014
572014
High speed sCMOS‐based oblique plane microscopy applied to the study of calcium dynamics in cardiac myocytes
MB Sikkel, S Kumar, V Maioli, C Rowlands, F Gordon, SE Harding, ...
Journal of biophotonics 9 (3), 311-323, 2016
452016
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