Ananya Paul
Ananya Paul
Research Scientist I, Georgia State University
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Chemistry and biology of DNA-binding small molecules
A Paul, S Bhattacharya
Current science, 212-231, 2012
Stabilization and structural alteration of the G-quadruplex DNA made from the human telomeric repeat mediated by Troger’s base based novel benzimidazole derivatives
A Paul, B Maji, SK Misra, AK Jain, K Muniyappa, S Bhattacharya
Journal of Medicinal Chemistry 55 (17), 7460-7471, 2012
Dimeric 1, 3-phenylene-bis (piperazinyl benzimidazole) s: synthesis and structure–activity investigations on their binding with human telomeric G-quadruplex DNA and telomerase …
AK Jain, A Paul, B Maji, K Muniyappa, S Bhattacharya
Journal of medicinal chemistry 55 (7), 2981-2993, 2012
Symmetrical bisbenzimidazoles with benzenediyl spacer: the role of the shape of the ligand on the stabilization and structural alterations in telomeric G-quadruplex DNA and …
S Bhattacharya, P Chaudhuri, AK Jain, A Paul
Bioconjugate chemistry 21 (7), 1148-1159, 2010
Synthesis and evaluation of a novel class of G-quadruplex-stabilizing small molecules based on the 1, 3-phenylene-bis (piperazinyl benzimidazole) system
AK Jain, VV Reddy, A Paul, S Bhattacharya
Biochemistry 48 (45), 10693-10704, 2009
Pharmacological inhibition of the transcription factor PU. 1 in leukemia
I Antony-Debré, A Paul, J Leite, K Mitchell, HM Kim, LA Carvajal, ...
The Journal of clinical investigation 127 (12), 4297-4313, 2017
Design, Synthesis, and DNA Binding Properties of Photoisomerizable Azobenzene− Distamycin Conjugates: An Experimental and Computational Study
S Ghosh, D Usharani, A Paul, S De, ED Jemmis, S Bhattacharya
Bioconjugate chemistry 19 (12), 2332-2345, 2008
Design and synthesis of heterocyclic cations for specific DNA recognition: from AT-rich to mixed-base-pair DNA sequences
Y Chai, A Paul, M Rettig, WD Wilson, DW Boykin
The Journal of organic chemistry 79 (3), 852-866, 2014
The thiophene “Sigma-Hole” as a concept for preorganized, specific recognition of G• C base pairs in the DNA minor groove
P Guo, A Paul, A Kumar, AA Farahat, D Kumar, S Wang, DW Boykin, ...
Chemistry (Weinheim an der Bergstrasse, Germany) 22 (43), 15404, 2016
Mixed up minor groove binders: Convincing A· T specific compounds to recognize a G· C base pair
A Paul, R Nanjunda, A Kumar, S Laughlin, R Nhili, S Depauw, SS Deuser, ...
Bioorganic & medicinal chemistry letters 25 (21), 4927-4932, 2015
The unusual monomer recognition of guanine-containing mixed sequence DNA by a dithiophene heterocyclic diamidine
M Munde, A Kumar, P Peixoto, S Depauw, MA Ismail, AA Farahat, A Paul, ...
Biochemistry 53 (7), 1218-1227, 2014
Understanding mixed sequence DNA recognition by novel designed compounds: The kinetic and thermodynamic behavior of azabenzimidazole diamidines
A Paul, Y Chai, DW Boykin, WD Wilson
Biochemistry 54 (2), 577-587, 2015
Binding of gemini bisbenzimidazole drugs with human telomeric G-quadruplex dimers: effect of the spacer in the design of potent telomerase inhibitors
A Paul, AK Jain, SK Misra, B Maji, K Muniyappa, S Bhattacharya
PLoS One 7 (6), e39467, 2012
A short DNA sequence confers strong bleomycin binding to hairpin DNAs
C Tang, A Paul, MP Alam, B Roy, WD Wilson, SM Hecht
Journal of the American Chemical Society 136 (39), 13715-13726, 2014
Systematic synthetic and biophysical development of mixed sequence DNA binding agents
A Paul, A Kumar, R Nanjunda, AA Farahat, DW Boykin, WD Wilson
Organic & biomolecular chemistry 15 (4), 827-835, 2017
Imino proton NMR guides the reprogramming of A• T specific minor groove binders for mixed base pair recognition
NK Harika, A Paul, E Stroeva, Y Chai, DW Boykin, MW Germann, ...
Nucleic acids research 44 (10), 4519-4527, 2016
Exploration of DAPI analogues: Synthesis, antitrypanosomal activity, DNA binding and fluorescence properties
AA Farahat, A Kumar, M Say, T Wenzler, R Brun, A Paul, WD Wilson, ...
European journal of medicinal chemistry 128, 70-78, 2017
Compound shape effects in minor groove binding affinity and specificity for mixed sequence DNA
P Guo, AA Farahat, A Paul, NK Harika, DW Boykin, WD Wilson
Journal of the American Chemical Society 140 (44), 14761-14769, 2018
A modular design for minor groove binding and recognition of mixed base pair sequences of DNA
P Guo, A Paul, A Kumar, NK Harika, S Wang, AA Farahat, DW Boykin, ...
Chemical Communications 53 (75), 10406-10409, 2017
Kinetics and structures on the molecular path to the quadruplex form of the human telomere
WD Wilson, A Paul
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