| Structure and folding of a designed knotted protein NP King, AW Jacobitz, MR Sawaya, L Goldschmidt, TO Yeates Proceedings of the National Academy of Sciences 107 (48), 20732-20737, 2010 | 149 | 2010 |
| Sortase transpeptidases: structural biology and catalytic mechanism AW Jacobitz, MD Kattke, J Wereszczynski, RT Clubb Advances in protein chemistry and structural biology 109, 223-264, 2017 | 141 | 2017 |
| Structural and computational studies of the Staphylococcus aureus sortase B-substrate complex reveal a substrate-stabilized oxyanion hole AW Jacobitz, J Wereszczynski, SW Yi, BR Amer, GL Huang, AV Nguyen, ... Journal of Biological Chemistry 289 (13), 8891-8902, 2014 | 50 | 2014 |
| Solution Structure of the Sortase Required for Efficient Production of Infectious Bacillus anthracis Spores SA Robson, AW Jacobitz, ML Phillips, RT Clubb Biochemistry 51 (40), 7953-7963, 2012 | 18 | 2012 |
| The “Lid” in the Streptococcus pneumoniae SrtC1 Sortase Adopts a Rigid Structure that Regulates Substrate Access to the Active Site AW Jacobitz, EB Naziga, SW Yi, SA McConnell, R Peterson, ME Jung, ... The Journal of Physical Chemistry B 120 (33), 8302-8312, 2016 | 17 | 2016 |
| Tryptophan oxidation of a monoclonal antibody under diverse oxidative stress conditions: distinct oxidative pathways favor specific tryptophan residues AW Jacobitz, Q Liu, S Suravajjala, NJ Agrawal Journal of Pharmaceutical Sciences 110 (2), 719-726, 2021 | 12 | 2021 |
| Advances in Protein Chemistry and Structural Biology AW Jacobitz, MD Kattke, J Wereszczynski, RT Clubb Academic Press Inc, 2017 | 12 | 2017 |
| Rapid addition of unlabeled silent solubility tags to proteins using a new substrate-fused sortase reagent BR Amer, R Macdonald, AW Jacobitz, B Liauw, RT Clubb Journal of biomolecular NMR 64, 197-205, 2016 | 11 | 2016 |
| Effects of buffer composition on site-specific glycation of lysine residues in monoclonal antibodies AW Jacobitz, AB Dykstra, C Spahr, NJ Agrawal Journal of Pharmaceutical Sciences 109 (1), 293-300, 2020 | 10 | 2020 |
| Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies M Mock, AW Jacobitz, CJ Langmead, A Sudom, D Yoo, SC Humphreys, ... MAbs 15 (1), 2256745, 2023 | 4 | 2023 |
| Utilizing cross-product prior knowledge to rapidly de-risk chemical liabilities in therapeutic antibody candidates AW Jacobitz, W Rodezno, NJ Agrawal AAPS Open 8 (1), 10, 2022 | 2 | 2022 |
| Structural and Computational Studies of the Staphylococcus Aureus Sortase B-Substrate Complex Provide New Insight into the Mechanism of Sortase Transpeptidases AW Jacobitz, J Wereszczynski, SW Yi, BR Amer, GL Huang, AV Nguyen, ... Biophysical Journal 106 (2), 677a, 2014 | 1 | 2014 |
| Utility of physiologically based pharmacokinetic modeling to predict inter-antibody variability in monoclonal antibody pharmacokinetics in mice S Liu, SC Humphreys, KD Cook, KP Conner, AR Correia, AW Jacobitz, ... Mabs 15 (1), 2263926, 2023 | | 2023 |
| Bispecific antibodies with cleavable c-terminal charge-paired tags JK Kawooya, AW Jacobitz, M Christopher, S Smith, K Graham, RLY Low, ... | | 2019 |
| The molecular basis of substrate recognition, catalysis, and regulation in sortase enzymes AW Jacobitz University of California, Los Angeles, 2015 | | 2015 |
Neil KingAssistant Professor, UW Biochemistry / Institute for Protein DesignE-mail confirmado em u.washington.edu
