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Alyna Katti
Alyna Katti
Revolution Medicines
E-mail confirmado em revmed.com
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Optimized base editors enable efficient editing in cells, organoids and mice
MP Zafra, EM Schatoff, A Katti, M Foronda, M Breinig, AY Schweitzer, ...
Nature biotechnology 36 (9), 888-893, 2018
3162018
CRISPR in cancer biology and therapy
A Katti, BJ Diaz, CM Caragine, NE Sanjana, LE Dow
Nature Reviews Cancer 22 (5), 259-279, 2022
2292022
Dietary fructose improves intestinal cell survival and nutrient absorption
SR Taylor, S Ramsamooj, RJ Liang, A Katti, R Pozovskiy, N Vasan, ...
Nature 597 (7875), 263-267, 2021
1632021
An In Vivo Kras Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants
MP Zafra, MJ Parsons, J Kim, D Alonso-Curbelo, S Goswami, EM Schatoff, ...
Cancer discovery 10 (11), 1654-1671, 2020
892020
Distinct colorectal cancer–associated apc mutations dictate response to tankyrase inhibition
EM Schatoff, S Goswami, MP Zafra, M Foronda, M Shusterman, BI Leach, ...
Cancer discovery 9 (10), 1358-1371, 2019
662019
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants
FJ Sánchez-Rivera, BJ Diaz, ER Kastenhuber, H Schmidt, A Katti, ...
Nature biotechnology 40 (6), 862-873, 2022
512022
GO: a functional reporter system to identify and enrich base editing activity
A Katti, M Foronda, J Zimmerman, B Diaz, MP Zafra, S Goswami, LE Dow
Nucleic acids research 48 (6), 2841-2852, 2020
312020
Generation of precision preclinical cancer models using regulated in vivo base editing
A Katti, A Vega-Pérez, M Foronda, J Zimmerman, MP Zafra, E Granowsky, ...
Nature Biotechnology 42 (3), 437-447, 2024
52024
Distinct colorectal cancer-associated APC mutations dictate response to tankyrase inhibition. Cancer Discov. 2019; 9: 1358–1371. doi: 10.1158/2159-8290
EM Schatoff, S Goswami, MP Zafra, M Foronda, M Shusterman, BI Leach, ...
CD-19-0289.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
5
Rapid generation of precision preclinical cancer models using regulatable in vivo base editing
A Katti, M Foronda, J Zimmerman, MP Zafra, S Goswami, EE Gardner, ...
bioRxiv, 2022.08. 03.502708, 2022
12022
Functional Common and Rare ERBB2 Germline Variants Cooperate in Familial and Sporadic Cancer Susceptibility
R Bao, A Ng, M Sasaki, M Esai Selvan, A Katti, H Lee, L Huang, AD Skol, ...
Cancer Prevention Research 14 (4), 441-454, 2021
12021
An optimized toolkit for precision base editing
MP Zafra, EM Schatoff, A Katti, M Foronda, M Breinig, AY Schweitzer, ...
bioRxiv, 303131, 2018
12018
Strategies to Improve the Engineering of Cancer Associated SNVs with Base Editing
A Katti
Weill Medical College of Cornell University, 2022
2022
Abstract PHA05: Strategies to improve engineering cancer-associated SNVs with base editing
A Katti, M Foronda, J Zimmerman, B Diaz, MP Zafra, S Goswami, ...
Cancer Research 80 (11_Supplement), PHA05-PHA05, 2020
2020
Base editing goes into hyperdrive
A Katti, LE Dow
Nature Cell Biology 22 (6), 617-618, 2020
2020
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