| Total biosynthesis of antitumor nonribosomal peptides in Escherichia coli K Watanabe, K Hotta, AP Praseuth, K Koketsu, A Migita, CN Boddy, ... Nature chemical biology 2 (8), 423-428, 2006 | 275 | 2006 |
| Differences in the risk of celiac disease associated with HLA-DQ2. 5 or HLA-DQ2. 2 are related to sustained gluten antigen presentation LE Fallang, E Bergseng, K Hotta, A Berg-Larsen, CY Kim, LM Sollid Nature immunology 10 (10), 1096-1101, 2009 | 171 | 2009 |
| Distinct mechanisms for spiro-carbon formation reveal biosynthetic pathway crosstalk Y Tsunematsu, N Ishikawa, D Wakana, Y Goda, H Noguchi, H Moriya, ... Nature Chemical Biology 9 (12), 818-825, 2013 | 138 | 2013 |
| Non‐Heme Dioxygenase Catalyzes Atypical Oxidations of 6, 7‐Bicyclic Systems To Form the 6, 6‐Quinolone Core of Viridicatin‐Type Fungal Alkaloids N Ishikawa, H Tanaka, F Koyama, H Noguchi, CCC Wang, K Hotta, ... Angewandte Chemie International Edition 53 (47), 12880-12884, 2014 | 118 | 2014 |
| Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis K Hotta, X Chen, RS Paton, A Minami, H Li, K Swaminathan, II Mathews, ... Nature 483 (7389), 355-358, 2012 | 111 | 2012 |
| Combinatorial generation of complexity by redox enzymes in the chaetoglobosin A biosynthesis K Ishiuchi, T Nakazawa, F Yagishita, T Mino, H Noguchi, K Hotta, ... Journal of the American Chemical Society 135 (19), 7371-7377, 2013 | 107 | 2013 |
| Siderophore-mediated iron acquisition in Bacillus anthracis and related strains K Hotta, CY Kim, DT Fox, AT Koppisch Microbiology 156 (7), 1918-1925, 2010 | 100 | 2010 |
| Precursor-Directed Biosynthesis of Epothilone in Escherichia c oli CN Boddy, K Hotta, ML Tse, RE Watts, C Khosla Journal of the American Chemical Society 126 (24), 7436-7437, 2004 | 89 | 2004 |
| Involvement of lipocalin‐like CghA in decalin‐forming stereoselective intramolecular [4+ 2] cycloaddition M Sato, F Yagishita, T Mino, N Uchiyama, A Patel, YH Chooi, Y Goda, ... ChemBioChem 16 (16), 2294-2298, 2015 | 87 | 2015 |
| Epothilone C macrolactonization and hydrolysis are catalyzed by the isolated thioesterase domain of epothilone polyketide synthase CN Boddy, TL Schneider, K Hotta, CT Walsh, C Khosla Journal of the American Chemical Society 125 (12), 3428-3429, 2003 | 82 | 2003 |
| Establishing a new methodology for genome mining and biosynthesis of polyketides and peptides through yeast molecular genetics K Ishiuchi, T Nakazawa, T Ookuma, S Sugimoto, M Sato, Y Tsunematsu, ... ChemBioChem 13 (6), 846-854, 2012 | 81 | 2012 |
| Cytochrome P450 as dimerization catalyst in diketopiperazine alkaloid biosynthesis T Saruwatari, F Yagishita, T Mino, H Noguchi, K Hotta, K Watanabe ChemBioChem 15 (5), 656-659, 2014 | 78 | 2014 |
| Nonspecific medium effects versus specific group positioning in the antibody and albumin catalysis of the base-promoted ring-opening reactions of benzisoxazoles Y Hu, KN Houk, K Kikuchi, K Hotta, D Hilvert Journal of the American Chemical Society 126 (26), 8197-8205, 2004 | 76 | 2004 |
| Structural and functional studies of trans-encoded HLA-DQ2. 3 (DQA1* 03: 01/DQB1* 02: 01) protein molecule S Tollefsen, K Hotta, X Chen, B Simonsen, K Swaminathan, II Mathews, ... Journal of Biological Chemistry 287 (17), 13611-13619, 2012 | 72 | 2012 |
| Elucidation of Pseurotin Biosynthetic Pathway Points to Trans‐Acting C‐Methyltransferase: Generation of Chemical Diversity Y Tsunematsu, M Fukutomi, T Saruwatari, H Noguchi, K Hotta, Y Tang, ... Angewandte Chemie 126 (32), 8615-8619, 2014 | 67 | 2014 |
| Yeast-based genome mining, production and mechanistic studies of the biosynthesis of fungal polyketide and peptide natural products Y Tsunematsu, K Ishiuchi, K Hotta, K Watanabe Natural Product Reports 30 (8), 1139-1149, 2013 | 67 | 2013 |
| Escherichia coli Allows Efficient Modular Incorporation of Newly Isolated Quinomycin Biosynthetic Enzyme into Echinomycin Biosynthetic Pathway for Rational … K Watanabe, K Hotta, M Nakaya, AP Praseuth, CCC Wang, D Inada, ... Journal of the American Chemical Society 131 (26), 9347-9353, 2009 | 65 | 2009 |
| The Missing Link in Petrobactin Biosynthesis: asbF Encodes a (-)-3-Dehydroshikimate Dehydratase DT Fox, K Hotta, CY Kim, AT Koppisch Biochemistry-Columbus 47 (47), 12251, 2010 | 58 | 2010 |
| Targeted Disruption of Transcriptional Regulators in Chaetomium globosum Activates Biosynthetic Pathways and Reveals Transcriptional Regulator-Like Behavior … T Nakazawa, K Ishiuchi, M Sato, Y Tsunematsu, S Sugimoto, Y Gotanda, ... Journal of the American Chemical Society 135 (36), 13446-13455, 2013 | 54 | 2013 |
| Echinomycin biosynthesis M Sato, T Nakazawa, Y Tsunematsu, K Hotta, K Watanabe Current opinion in chemical biology 17 (4), 537-545, 2013 | 54 | 2013 |
