Jeremy Owen
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Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens
BM Hover, SH Kim, M Katz, Z Charlop-Powers, JG Owen, MA Ternei, ...
Nature microbiology 3 (4), 415-422, 2018
1872018
Mapping gene clusters within arrayed metagenomic libraries to expand the structural diversity of biomedically relevant natural products
JG Owen, BVB Reddy, MA Ternei, Z Charlop-Powers, PY Calle, JH Kim, ...
Proceedings of the National Academy of Sciences 110 (29), 11797-11802, 2013
982013
Global biogeographic sampling of bacterial secondary metabolism
Z Charlop-Powers, JG Owen, BVB Reddy, MA Ternei, DO Guimarães, ...
Elife 4, e05048, 2015
972015
Chemical-biogeographic survey of secondary metabolism in soil
Z Charlop-Powers, JG Owen, BVB Reddy, MA Ternei, SF Brady
Proceedings of the National Academy of Sciences 111 (10), 3757-3762, 2014
942014
Multiplexed metagenome mining using short DNA sequence tags facilitates targeted discovery of epoxyketone proteasome inhibitors
JG Owen, Z Charlop-Powers, AG Smith, MA Ternei, PY Calle, BVB Reddy, ...
Proceedings of the National Academy of Sciences 112 (14), 4221-4226, 2015
812015
Secondary metabolism in the lichen symbiosis
MJ Calcott, DF Ackerley, A Knight, RA Keyzers, JG Owen
Chemical Society Reviews 47 (5), 1730-1760, 2018
582018
A functional screen for recovery of 4′‐phosphopantetheinyl transferase and associated natural product biosynthesis genes from metagenome libraries
JG Owen, KJ Robins, NS Parachin, DF Ackerley
Environmental microbiology 14 (5), 1198-1209, 2012
572012
Characterization of pyoverdine and achromobactin in Pseudomonas syringae pv. phaseolicola 1448a
JG Owen, DF Ackerley
BMC microbiology 11 (1), 1-16, 2011
522011
Rapid and flexible biochemical assays for evaluating 4′-phosphopantetheinyl transferase activity
JG Owen, JN Copp, DF Ackerley
Biochemical Journal 436 (3), 709-717, 2011
482011
Biosynthesis of novel Pyoverdines by domain substitution in a nonribosomal peptide synthetase of Pseudomonas aeruginosa
MJ Calcott, JG Owen, IL Lamont, DF Ackerley
Applied and environmental microbiology 80 (18), 5723-5731, 2014
442014
Structure, function, and biosynthetic origin of octapeptin antibiotics active against extensively drug-resistant Gram-negative bacteria
T Velkov, A Gallardo-Godoy, JD Swarbrick, MAT Blaskovich, AG Elliott, ...
Cell chemical biology 25 (4), 380-391. e5, 2018
362018
Structural, functional and evolutionary perspectives on effective re-engineering of non-ribosomal peptide synthetase assembly lines
AS Brown, MJ Calcott, JG Owen, DF Ackerley
Natural product reports 35 (11), 1210-1228, 2018
342018
Marine invertebrate natural products that target microtubules
JH Miller, JJ Field, A Kanakkanthara, JG Owen, AJ Singh, PT Northcote
Journal of natural products 81 (3), 691-702, 2018
332018
Generating functional recombinant NRPS enzymes in the laboratory setting via peptidyl carrier protein engineering
JG Owen, MJ Calcott, KJ Robins, DF Ackerley
Cell chemical biology 23 (11), 1395-1406, 2016
242016
Selective enrichment of environmental DNA libraries for genes encoding nonribosomal peptides and polyketides by phosphopantetheine transferase-dependent complementation of …
Z Charlop-Powers, JJ Banik, JG Owen, JW Craig, SF Brady
ACS chemical biology 8 (1), 138-143, 2013
242013
Old dogs and new tricks in antimicrobial discovery
MS Butler, MAT Blaskovich, JG Owen, MA Cooper
Current opinion in microbiology 33, 25-34, 2016
172016
Uncovering the biosynthetic potential of rare metagenomic DNA using co-occurrence network analysis of targeted sequences
V Libis, N Antonovsky, M Zhang, Z Shang, D Montiel, J Maniko, MA Ternei, ...
Nature communications 10 (1), 1-9, 2019
142019
Proteomics quantifies protein expression changes in a model cnidarian colonised by a thermally tolerant but suboptimal symbiont
AE Sproles, CA Oakley, JL Matthews, L Peng, JG Owen, AR Grossman, ...
The ISME journal 13 (9), 2334-2345, 2019
112019
Efficient rational modification of non-ribosomal peptides by adenylation domain substitution
MJ Calcott, JG Owen, DF Ackerley
Nature communications 11 (1), 1-10, 2020
72020
Metagenomic exploration of the marine sponge Mycale hentscheli uncovers multiple polyketide-producing bacterial symbionts
MA Storey, SK Andreassend, J Bracegirdle, A Brown, RA Keyzers, ...
Mbio 11 (2), 2020
62020
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