‘Click chemistry’synthesis of a library of 1, 2, 3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface trans-sialidase I Carvalho, P Andrade, VL Campo, PMM Guedes, R Sesti-Costa, JS Silva, ... Bioorganic & medicinal chemistry 18 (7), 2412-2427, 2010 | 171 | 2010 |
Neutralisation of SARS-CoV-2 lineage P. 1 by antibodies elicited through natural SARS-CoV-2 infection or vaccination with an inactivated SARS-CoV-2 vaccine: an immunological study WM Souza, MR Amorim, R Sesti-Costa, LD Coimbra, NS Brunetti, ... The Lancet Microbe 2 (10), e527-e535, 2021 | 109 | 2021 |
Non-peptidic cruzain inhibitors with trypanocidal activity discovered by virtual screening and in vitro assay HJ Wiggers, JR Rocha, WB Fernandes, R Sesti-Costa, ZA Carneiro, ... PLoS neglected tropical diseases 7 (8), e2370, 2013 | 103 | 2013 |
Apoptosis-associated Speck–like protein containing a caspase recruitment domain inflammasomes mediate IL-1β response and host resistance to Trypanosoma cruzi infection GK Silva, RS Costa, TN Silveira, BC Caetano, CV Horta, FRS Gutierrez, ... The Journal of Immunology 191 (6), 3373-3383, 2013 | 102 | 2013 |
In vitro activation of mouse neutrophils by recombinant human interferon-gamma: increased phagocytosis and release of reactive oxygen species and pro-inflammatory cytokines LF Marchi, R Sesti-Costa, MDC Ignacchiti, S Chedraoui-Silva, ... International immunopharmacology 18 (2), 228-235, 2014 | 72 | 2014 |
Design, synthesis and the effect of 1, 2, 3-triazole sialylmimetic neoglycoconjugates on Trypanosoma cruzi and its cell surface trans-sialidase VL Campo, R Sesti-Costa, ZA Carneiro, JS Silva, S Schenkman, ... Bioorganic & medicinal chemistry 20 (1), 145-156, 2012 | 69 | 2012 |
Chronic cold stress in mice induces a regulatory phenotype in macrophages: correlation with increased 11β-hydroxysteroid dehydrogenase expression R Sesti-Costa, MDC Ignacchiti, S Chedraoui-Silva, LF Marchi, ... Brain, Behavior, and Immunity 26 (1), 50-60, 2012 | 64 | 2012 |
6-Mercaptopurine complexes with silver and gold ions: anti-tuberculosis and anti-cancer activities A Cuin, AC Massabni, GA Pereira, CQF Leite, FR Pavan, R Sesti-Costa, ... Biomedicine & Pharmacotherapy 65 (5), 334-338, 2011 | 64 | 2011 |
The IL-33/ST2 pathway controls Coxsackievirus B5–induced experimental pancreatitis R Sesti-Costa, GK Silva, JL Proença-Módena, D Carlos, ML Silva, ... The Journal of Immunology 191 (1), 283-292, 2013 | 56 | 2013 |
Glycoclusters presenting lactose on calix [4] arene cores display trypanocidal activity E Galante, C Geraci, S Sciuto, VL Campo, I Carvalho, R Sesti-Costa, ... Tetrahedron 67 (33), 5902-5912, 2011 | 48 | 2011 |
In Vitro and In Vivo Trypanocidal Activity of H2bdtc-Loaded Solid Lipid Nanoparticles ZA Carneiro, PI da S. Maia, R Sesti-Costa, CD Lopes, TA Pereira, ... PLoS Neglected Tropical Diseases 8 (5), e2847, 2014 | 47 | 2014 |
Oropouche virus infection and pathogenesis are restricted by MAVS, IRF-3, IRF-7, and type I interferon signaling pathways in nonmyeloid cells JL Proenca-Modena, R Sesti-Costa, AK Pinto, JM Richner, HM Lazear, ... Journal of virology 89 (9), 4720-4737, 2015 | 46 | 2015 |
1, 2, 3-Triazole-based analogue of benznidazole displays remarkable activity against Trypanosoma cruzi P de Andrade, OA Galo, MR Carvalho, CD Lopes, ZA Carneiro, ... Bioorganic & Medicinal Chemistry 23 (21), 6815-6826, 2015 | 45 | 2015 |
SARS-CoV-2 uses CD4 to infect T helper lymphocytes GG Davanzo, AC Codo, NS Brunetti, VO Boldrini, TL Knittel, LB Monterio, ... | 43* | 2020 |
Effects of acute cold stress on phagocytosis of apoptotic cells: the role of corticosterone R Sesti-Costa, GC Baccan, S Chedraoui-Silva, B Mantovani Neuroimmunomodulation 17 (2), 79-87, 2010 | 43 | 2010 |
COVID-19 content collection WM Souza, MR Amorim, R Sesti-Costa, LD Coimbra, NS Brunetti, ... The Lancet 398 (10297), 2021 | 41 | 2021 |
Ruthenium complex with benznidazole and nitric oxide as a new candidate for the treatment of chagas disease R Sesti-Costa, ZA Carneiro, MC Silva, M Santos, GK Silva, C Milanezi, ... PLoS neglected tropical diseases 8 (10), e3207, 2014 | 34 | 2014 |
Histopathological correlates of global and segmental left ventricular systolic dysfunction in experimental chronic Chagas cardiomyopathy LFL de Oliveira, MMD Romano, EEV de Carvalho, J Mejia Cabeza, ... Journal of the American Heart Association 5 (1), e002786, 2016 | 33 | 2016 |
B lymphocyte–induced maturation protein 1 controls TH9 cell development, IL-9 production, and allergic inflammation L Benevides, RS Costa, LA Tavares, M Russo, GA Martins, LLP da Silva, ... Journal of Allergy and Clinical Immunology 143 (3), 1119-1130. e3, 2019 | 30 | 2019 |
Microbiota induces tonic CCL2 systemic levels that control pDC trafficking in steady state M Swiecki, HL Miller, R Sesti-Costa, M Cella, S Gilfillan, M Colonna Mucosal immunology 10 (4), 936-945, 2017 | 30 | 2017 |